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The use of dendrimers for gene delivery is a promising strategy in gene therapy. These highly branched, nanometric polymers can efficiently encapsulate nucleic acids and facilitate their transportation into target cells. Dendrimers offer controlled release properties and can be modified for targeted delivery, enhancing the selectivity and efficacy of gene therapies. Their multivalency allows for multiple functional groups, enabling the simultaneous delivery of genes and therapeutic agents. This innovative approach could significantly advance the treatment of genetic disorders and various diseases, providing a robust platform for future therapeutic applications.